The DSW International Affairs Office in Brussels, Belgium, was established in January 2000.

Located near the European Parliament in the historic Place du Luxembourg, the International Affairs Office supports and advises DSW and other NGOs regarding policy and funding developments related to the European institutions, European-level consortia, foundations and other international institutions.

DSW maintains contact with the European Commission (EC) and members of the European Parliament, as well as with representatives of other non-governmental organisations (NGOs) and international organisations.

The purpose of the International Affairs Office is to provide education and conduct advocacy for improved European Union and global policies, as well as to promote better channelling funds affecting global health and population concerns. It serves as a central liaison point for Brussels-based and Southern NGOs working on population, sexual and reproductive health (SRH), HIV/AIDS and related health problems in developing countries.